Home \ Faculty Details \ Ercan Bursal
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  • Email:

    ebursal@pmu.edu.sa

  • Office No:

    S020

  • Ercan Bursal

  • Job Title :

    Professor

  • College :

    Deanship of Research


  • Department :

    Deanship of Research


Dr. Ercan Bursal earned his PhD degree in Biochemistry from Ataturk University, Turkey, in 2009.

He conducted postdoctoral research at Texas Tech University, Department of Chemistry and Biochemistry, from 2016 to 2017.

He started his teaching career as a “Science Teacher”, serving in this role from 2000 to 2010. After receiving his Ph.D., he worked as an “Assist. Prof.” and “Assoc. Prof.” titles in 2010-2017 at Mus Alparslan University, Faculty of Science in Turkey. In 2017, he was promoted to “Full Professor” at the Faculty of Health, Mus Alparslan University.

Currently, he serves as a “Full Research Professor” at the College of Engineering, Prince Mohammad bin Fahd University.

Dr. Ercan Bursal has authored more than 70 articles in SCI-indexed journals on his research area with having more than 5400 citations and 35 h-index. He is the coauthor of 20 book chapters, as well. He supervised one Ph.D. and seven M.S. students.

The main topics of his studies are antioxidant activity, bioorganic compounds, medicinal plants, enzyme activity/inhibition, and biochemical parameters in biological samples. Also, his main specializations are UV-Spectrophotometry, HPLC, and LC-MS-MS.

He is a member of editorial boards of over 15 journals and frequently reviews for numerous international SCI journals.

Beyond being a researcher, he has extensive teaching experience in courses, such as General Chemistry, Biochemistry, Analytical Chemistry, Organic Chemistry, and some Lab courses.

Recognized among the world’s top 2% of scientists in Chemistry from 2021 to 2024.

B. Sc. (1996-2000): Yuzuncu Yil University, Faculty of Education, Department of Chemistry, Van, Turkey.

M. Sc. (2000-2004): Yuzuncu Yil University, Faculty of Medicine, Department of Biochemistry, Van, Turkey. 

Ph. D. (2005-2009): Ataturk University, Faculty of Science, Department of Chemistry (Biochemistry), Erzurum, Turkey.

Post Doc (2016-2017): Texas Tech University, Department of Chemistry and Biochemistry, Lubbock, Texas, USA.

  1. Noyan, T., Bursal, E., Şekeroğlu, M.R., Dülger, H., Kamacı, M., (2006). The serum interleukin-6 and tumor necrosis factor-a levels and their relationship with antithrombin-III and von willebrand factor in preeclampsia. Journal of the Turkish-German Gynecological Association, Vol 7(1): 39-44.
  2. Köksal, E., Gülçin, İ., Öztürk Sarıkaya, S.B., Bursal, E. (2009). In vitro antioxidant activity of silymarin. Journal of Enzyme Inhibition and Medicinal Chemistry, 24(2): 395-405.
  3. Gülçin, İ., Bursal, E., Şehitoğlu H.M., Bilsel, M., Gören, A.C. (2010). Polyphenol contents and antioxidant activity of lyophilized aqueous extract of propolis from Erzurum, Turkey. Food and Chemical Toxicology, 48, 2227-2238.
  4. Köksal, E., Bursal, E., Dikici, E., Tozoğlu, F., Gülçin, İ. (2011). Antioxidant activity of Melissa officinalis leaves. Journal of Medicinal Plants Research, 5 (2): 217-222.
  5. Gülçin, İ., Topal, F., Öztürk Sarıkaya, S.B., Bursal, E., Bilsel, G., Gören, A.C. (2011). Polyphenol contents and antioxidant properties of medlar (Mespilus germanica L.). Records of Natural Products, 5(3): 158-175.
  6. Bursal, E., Köksal, E. (2011). Evaluation of reducing power and radical scavenging activities of water and ethanol extracts from sumac (Rhus coriaria L.). Food Research International, 44 (7): 2217-2221.
  7. Bursal, E., Gülçin, İ. (2011). Polyphenol contents and in vitro antioxidant activities of lyophilised aqueous extract of kiwifruit (Actinidia deliciosa). Food Research International, 44 (5), 1482-1489.
  8. Köksal, E., Bursal, E., Aggül, A.G., Gülçin, İ. (2012). Purification and characterization of peroxiase from sweet gourd. International Journal of Food Properties,15 (5), 1110-1119.
  9. Bursal, E. (2013). Kinetic properties of peroxidase enzyme from chard (Beta vulgaris subspecies cicla). International Journal of Food Properties, 16 (6), 1293-1303.
  10. Bursal, E., Köksal, E., Gülçin, İ., Bilsel, G., Gören, A.C. (2013). Antioxidant activity and polyphenol content of cherry stem (Cerasus avium L.) determined by LC–MS/MS. Food Research International 51, 66-74.
  11. Güzel, E., Boğa, R., Bursal, E. (2013). Determination of antioxidant activities of Asphodelus aestivus. Muş Alparslan University Journal of Science, 1 (1), 17-25.
  12. Işık, M., Korkmaz, M., Bursal, E., Gülçin, İ., Köksal, E., Tohma, H. (2015). Determination of antioxidant properties of Gypsophila bitlisensis bark. International Journal of Pharmacology, 11 (4), 366-371.
  13. Turan, N., Bursal, E., Çolak, N., Buldurun, K. (2015). Investigation of synthesis, structural characterization, antioxidant activities and thermal properties of Zn(II), Fe(II) and Mn(II) complexes with thiophene-carboxylate ligand. Journal of Chemistry and Biochemistry, 3(2): 13-29.
  14. Aras, A., Bursal, E., Doğru, M. (2016). UHPLC-ESI-MS/MS analyses for quantification of phenolic compounds of Nepeta nuda subsp. Lydiae. Journal of Applied Pharmaceutical Science, 6 (11): 9-13.
  15. Aras, A., Doğru, M., Bursal, E. (2016). Determination of antioxidant potential of Nepeta nuda subsp. lydiae. Analytical Chemistry Letters. 6 (6): 758-765.
  16. Turan, N., Adıgüzel, R., Buldurun, K., Bursal, E. (2016). Spectroscopic, thermal and antioxidant properties of novel mixed ligand-metal complexes obtained from saccharinate complexes and azo dye ligand (mnppa). International Journal of Pharmacology, 12(2): 92-100.
  17. Tohma, H., Koksal, E., Kilic, O, Alan, Y., Yılmaz, M.A., Gulcin, I, Bursal, E., Alwasel, S. (2016). RP-HPLC/MS/MS analysis of the phenolic compounds, antioxidant and antimicrobial activities of Salvia L. species. Antioxidants, 5 (4): 38.
  18. Köksal, E., Bursal, E., Gülçin, İ., Korkmaz, M., Çağlayan, C., Gören, A.C., Alwasel, S.H. (2017). Antioxidant activity and polyphenol content of Turkish thyme (Thymus vulgaris) monitored by LCMS/MS. International Journal of Food Properties. 20(3): 514-525.
  19. Tohma, H., Gulcin, I., Bursal, E., Goren, A.C., Alwasel, S., Koksal, E. (2017). Antioxidant activity and phenolic compounds of ginger (Zingiber officinale Rosc.) determined by HPLC-MS/MS. Journal of Food Measurement and Characterization, 11: 556-566.
  20. Koksal, E., Tohma, H., Kilic, O, Alan, Y., Aras, A., Gulcin, I, Bursal, E., (2017). Assessment of antioxidant and antimicrobial activities of Nepeta trachonitica - Analysis of its phenolic compounds using HPLC-MS/MS. Scientia Pharmaceutica, 85, 24.
  21. Aras, A., Silinsin, M., Bingol, M.N., Bursal, E. (2017). Identification of bioactive polyphenolic compounds and assessment of antioxidant activity of Origanum acutidens. International Letters of Natural Sciences, 66, 1-8.
  22. Boğa, R., Bursal, E. (2018). Polyphenols analysed by UHPLC-ESI-MS/MS and antioxidant activities of molasses, acorn and leaves of oak (Quercus robur subsp. pedunculiflora). Progress in Nutrition. 20 (1S): 167-175.
  23. Silinsin, M., Bursal, E. (2018). UHPLC-MS/MS phenolic profiling and in vitro antioxidant activities of Inula graveolens (L.) Desf. Natural Product Research, 32 (12): 1467-1471.
  24. Bingol, M.N., Bursal, E. (2018). LC-MS/MS Analysis of phenolic compounds and in vitro antioxidant potential of Stachys lavandulifolia Vahl. Var. brachydon Boiss. International Letters of Natural Sciences, 72, 28-36.
  25. Aras, A., Bursal, E., Alan, Y., Turkan, F., Alkan, H., Kilic, O. (2018). Polyphenolic contents, antioxidant potential and antimicrobial activity of Satureja boissieri. Iranian Journal of Chemistry and Chemical Engineering. 37 (6), 209-219.
  26. Bursal, E., Aras, A., Kilic, O. (2019). Evaluation of antioxidant capacity of endemic plant Marrubium astracanicum subsp. macrodon: Identification of its phenolic contents by using HPLC-MS/MS. Natural Product Research, 13, 1975-1979.
  27. Bursal, E., Aras, A., Kılıç, Ö., Taslimi, P., Gören, A.C., Gülçin, İ. (2019). Phytochemical content, antioxidant activity and enzyme inhibition effect of Salvia eriophora Boiss. & Kotschy against acetylcholinesterase, α-amylase, butyrylcholinesterase and α-glycosidase enzymes. Journal of Food Biochemistry, 43, 3, e12776.
  28. Banazadaeh Alireza, Nieman Reed, Goli Mona, Peng, Wenjing, Hussien, Ahmed, Bursal Ercan, Lischka Hans, Mechref Yehia. (2019). Characterization of glycan isomers using magnetic carbon nanoparticles as a MALDI co-matrix. RSC Advances, 9(35), 20137-20148.
  29. Buldurun, K., Turan, N., Aras, A., Mantarcı, A., Turkan, F., Bursal, E., (2019). Spectroscopic and structural characterization, enzyme ınhibitions, and antioxidant effects of new Ru(II) and Ni(II) complexes of Schiff base. Chemistry & Biodiversity, 16, (8), e1900243.
  30. Aras, A., Bursal, E., Turkan. F., Tohma, H., Kılıç, Ö., Gülçin, İ., Koksal, E. (2019). Phytochemical content, antidiabetic, anticholinergic, antioxidant activities of endemic Lecokia cretica extracts. Chemistry & Biodiversity, 16,e1900341.
  31. Buldurun, K., Turan, N., Bursal, E., Mantarcı, A., Turkan, F., Taslimi, P., Gülçin, İ. (2020). Synthesis, spectroscopic properties, crystal structures, antioxidant activities and enzyme inhibition determination of Co(II) and Fe(II) complexes of Schiff base. Research on Chemical Intermediates, 46 (1), 283-297.
  32. Türkan, F., Atalar, M.N., Aras, A., Gülçin, İ., Bursal, E. (2020). ICP-MS and HPLC analyses, enzyme inhibition and antioxidant potential of Achillea schischkinii Sosn. Bioorganic Chemistry, 94, 10333
  33. Gülçin, İ., Gören, A.C., Taslimi, P., Elwasel, S., Kılıç, Ö., Bursal, E. (2020). Anticholinergic, antidiabetic and antioxidant activities of Anatolian pennyroyal (Mentha pulegium)-analysis of its polyphenol contents by LC-MS/MS. Biocatalysis and Agricultural Biotechnology, 23, 101441.
  34. Koksal, E., Taslimi, P., Gören, A.C., Bursal, E., Aras, A., Kılıç, Ö, Elwasel, S., Gülçin, İ. (2020). Anti-Alzheimer, antidiabetic and antioxidant potential of Satureja cuneifolia and analysis of its phenolic contents by LC-MS/MS, Arabian Journal of Chemistry, 13 (3), 4528-4537.
  35. Teber, İ., Bursal, E. (2020). Phenolic compounds and antioxidant activity of Nepeta nuda subsp. albiflora. International Letters of Natural Sciences, 79, 1-8.
  36. Bursal, E., Taslimi, P., Gören, A.C., Gülçin, İ. (2020). Assessments of anticholinergic, antidiabetic, antioxidant activities and phenolic content of Stachys annua. Biocatalysis and Agricultural Biotechnology 28, 101711.
  37. Aras, A., Türkan, F., Yildiko, U., Atalar, M.N., Kılıç, Ö., Alma, M.H., Bursal, E. (2021). Biochemical constituent, enzyme inhibitory activity, and molecular docking analysis of an endemic plant species, Thymus migricus. Chemical Papers, 75, 1133-1146.
  38. Bursal, E.,Turkan, F., Buldurun, K., Turan, N., Aras, A., Colak, N., Murahari, M., Yergeri, M.C. (2021). Transition metal complexes of a multidentate Schiff base ligand containing pyridine:synthesis, characterization, enzyme inhibitions, antioxidant properties, and molecular docking studies. Biometals, 34: 393-406.
  39. Bursal, E., Yılmaz, M.A., Aras, A., Türkan, F., Yildiko, U., Kılıç, Ö., Dey, A. (2021). Determination of phenolic content, biological activity, and enzyme inhibitory properties with molecular docking studies of Rumex nepalensis, an endemic medicinal plant, Journal of Food and Nutrition Research, 9(3): 114-123.
  40. Bursal, E., Aras, A., Kılıç, Ö., Buldurun, K. (2021). Chemical constituent and radical scavenging antioxidant activity of Anthemis kotschyana Boiss. Natural Product Research, 35 (22), 4794-4797.
  41. Buldurun, K., Turan, N., Bursal, E., Aras, A., Mantarcı, A., Çolak, N., Türkan, F. and Gülçin, İ., (2021). Synthesis, characterization, powder X-ray diffraction analysis, thermal stability, antioxidant properties and enzyme inhibitions of M (II)-Schiff base ligand complexes. Journal of Biomolecular Structure and Dynamics, 39(17), 6480-6487.
  42. Ullah SA, Zafar M, Ahmad M, Ghufran MA, Bursal E, Kilic O, Sultana S, Yaseen G, Khan S, Majeed S. (2021). Microscopic implication and evaluation of herbaceous melliferous plants of southern Khyber Pakhtunkhwa‐Pakistan using light and scanning electron microscope. Microscopy Research and Technique. 84(8):1750-1764.
  43. Cetin, A., Türkan, F., Bursal, E., Murahari, M. (2021). Synthesis, characterization, enzyme inhibitions, and molecular docking analysis of a new series of thiophene based heterocyclic compounds. Russian Journal of Organic Chemistry. 57 (4), 598-604.
  44. Kaya, E., Erdoğan, E., Bursal, E., & Canpolat, E. (2021). Synthesis, characterization, optical, morphological, and antioxidant properties of oligo (2-ethoxy-6-(((2-hydroxyphenyl) imino) methyl) phenol) obtained by oxidative polycondensation. Iranian Polymer Journal, 30, 285-295.
  45. Turan, N., Buldurun, K., Adiguzel, R., Aras, A., Turkan, F., & Bursal, E. (2021). Investigation of spectroscopic, thermal, and biological properties of FeII, CoII, ZnII, and RuII complexes derived from azo dye ligand. Journal of Molecular Structure, 1244, 130989.
  46. Bursal, E., Yilmaz, M. A., Izol, E., Türkan, F., Atalar, M. N., Murahari, M., Aras, A., & Ahmad, M. (2021). Enzyme inhibitory function and phytochemical profile of Inula discoidea using in vitro and in silico methods. Biophysical Chemistry, 106629.
  47. Cetin, A., Bursal, E., & Türkan, F. (2021). 2-methylindole analogs as cholinesterases and glutathione S-transferase inhibitors: Synthesis, biological evaluation, molecular docking, and pharmacokinetic studies. Arabian Journal of Chemistry, 14(12), 103449.
  48. Korkmaz, A., & Bursal, E. (2022). Benzothiazole sulfonate derivatives bearing azomethine: Synthesis, characterization, enzyme inhibition, and molecular docking study. Journal of Molecular Structure, 1257, 132641.
  49. Korkmaz, A., & Bursal, E. (2022). An in vitro and in silico study on the synthesis and characterization of novel bis (sulfonate) derivatives as tyrosinase and pancreatic lipase inhibitors. Journal of Molecular Structure, 1259, 132734.
  50. Korkmaz, A., & Bursal, E. (2022). Synthesis, biological activity and molecular docking studies of novel sulfonate derivatives bearing salicylaldehyde. Chemistry & Biodiversity, 19(6), e202200140.
  51. Ghorai, M., Kumar, V., Kumar, V., Al-Tawaha, A.R., Shekhawat, M.S., Pandey, D.K., Batiha, G.E.S., Bursal, E., Jha, N.K., Gadekar, V.S. and Radha, (2022). Beneficial role of selenium (se) biofortification in developing resilience against potentially toxic metal and metalloid Stress in crops: recent trends in genetic engineering and omics approaches. Journal of Soil Science and Plant Nutrition, 22(2), pp.2347-2377.
  52. Banerjee, S., Lo, W.C., Majumder, P., Roy, D., Ghorai, M., Shaikh, N.K., Kant, N., Shekhawat, M.S., Gadekar, V.S., Ghosh, S. and Bursal, E., (2022). Multiple roles for basement membrane proteins in cancer progression and EMT. European Journal of Cell Biology, 101(2), 151220.
  53. Turan, N., Buldurun, K., Bursal, E., & Mahmoudi, G. (2022). Pd (II)-Schiff base complexes: Synthesis, characterization, Suzuki–Miyaura and Mizoroki–Heck cross-coupling reactions, enzyme inhibition and antioxidant activities. Journal of Organometallic Chemistry, 970, 122370.
  54. Balcı, N., Şakiroğlu, H., Türkan, F. and Bursal, E., (2022). In vitro and in silico enzyme inhibition effects of some metal ions and compounds on glutathione S-transferase enzyme purified from Vaccinium arctostapylous L. Journal of Biomolecular Structure and Dynamics, 40(22), 11587-11593.
  55. Buldurun, K., Aras, A., Turan, N., Turkan, F., Adiguzel, R. and Bursal, E., (2022). Synthesis and Characterization of Azo Dye Complexes as Potential Inhibitors of Acetylcholinesterase, Butyrylcholinesterase, and Glutathione S‐Transferase. ChemistrySelect, 7(40), p.e202203365.
  56. Turan, N., Buldurun, K., Türkan, F., Aras, A., Çolak, N., Murahari, M., Bursal, E. and Mantarcı, A., 2022. Some metal chelates with Schiff base ligand: Synthesis, structure elucidation, thermal behavior, XRD evaluation, antioxidant activity, enzyme inhibition, and molecular docking studies. Molecular Diversity, 26, 2459–2472.
  57. Buldurun, K., Turan, N., Mahmoudi, G. and Bursal, E., (2022). Half-sandwich ruthenium (II)(η6-p-cymene) complexes: Syntheses, characterization, transfer hydrogenation reactions, antioxidant and enzyme inhibitory activities. Journal of Molecular Structure, 1262, 133075.
  58. Türkan, F., Taslimi, P., Cabir, B., Ağırtaş, M.S., Erden, Y., Celebioglu, H.U., Tuzun, B., Bursal, E. and Gulcin, I., (2022). Co and Zn Metal phthalocyanines with bulky substituents: Anticancer, antibacterial activities and their inhibitory effects on some metabolic enzymes with molecular docking studies. Polycyclic Aromatic Compounds, 42(7), pp.4475-4486.
  59. Korkmaz, A., Bursal, E.,  Kurtay, G. (2023). In Vitro and In Silico Evaluation of Amylase, Tyrosinase, and Pancreatic Lipase Inhibitions of Novel Benzothiazole‐Sulfonate Derivatives. ChemistrySelect, 8(42), e202302936.
  60. Medetalibeyoğlu, H., Türkan, F., Manap, S., Bursal, E., Beytur, M., Aras, A., Akyıldırım, O., Kotan, G., Gürsoy-Kol, Ö. Yüksek, H., (2023). Synthesis and acetylcholinesterase enzyme inhibitory effects of some novel 4, 5-Dihydro-1 H-1, 2, 4-triazol-5-one derivatives; an in vitro and in silico study. Journal of Biomolecular Structure and Dynamics, 41(10), 4286-4294.
  61. Balcı, N., Çelik, H., Türkan, F., Çelebioğlu, N., Çelik, T., Bursal, E. (2023). Schiff Base Synthesis with a New Reliable Method and Investigation of Their Inhibition Effects on Glutathione S‐Transferase and Cholinesterase Enzymes. ChemistrySelect, 8(18), e202204566.
  62. Elmusa, M., Elmusa, S., Mert, S., Kasımoğulları, R., Türkan, F., Atalar, M.N. Bursal, E., (2023). One-pot three-component synthesis of novel pyrazolo-acridine derivatives and assessment of their acetylcholinesterase inhibitory properties: An in vitro and in silico study. Journal of Molecular Structure, 1274, 134553.
  63. Yılmaz, M.A., Taslimi, P., Kılıç, Ö., Gülçin, İ., Dey, A., Bursal, E., (2023). Unravelling the phenolic compound reserves, antioxidant and enzyme inhibitory activities of an endemic plant species, Achillea pseudoaleppica. Journal of Biomolecular Structure and Dynamics, 41(2), 445-456.
  64. Korkmaz, A., Kurtay, G., Kaya, E., Bursal, E., (2023). Design, synthesis, spectroscopic characterizations, in vitro pancreatic lipase as well as tyrosinase inhibition evaluations and in silico analysis of novel aryl sulfonate-naphthalene hybrids. Journal of Biomolecular Structure and Dynamics, 41, 7128-7143.
  65. Aslan, H., Yetişsin, F., Korkmaz, A., Bursal, E. (2024). Design, Synthesis, Characterization, Enzyme Inhibition, Molecular Docking, and Pharmacological Evaluation of New Chalcone‐Sulfonate Derivatives Bearing Thiophene. ChemistrySelect, 9(14), e202400053.
  66. İzol, E., Bursal, E., Yapıcı, İ., Abdullah Yilmaz, M., Yilmaz, İ., & Gülçin, İ. (2024). Chemical Content by LC–MS/MS, Antiglaucoma, and Antioxidant Activity of Propolis Samples From Different Regions of Türkiye. Journal of Food Biochemistry, 2024(1), 7488590.

 

Prince Mohammad bin Fahd University, College of Engineering, Department of Chemical Engineering, Al Khobar, Saudi Arabia

  1. 2001-2010: Science Teacher (government schools in Turkey)
  2. 2010-2012: Assist. Prof. Dr. (Muş Alparslan University, Faculty of Science, Department of Chemistry, Mus, Turkey)
  3. 2012-2017: Assoc. Prof. Dr. (Muş Alparslan University, School of Health Services, Mus, Turkey)
  4. 2016-2017: Visiting Scholar, Research Professor (Texas Tech University, Lubbock, TX, USA)
  5. 2017- 2024: Full Professor Muş Alparslan University, Faculty of Health, Muş, Turkey
  6. 2025-present: Full Research Professor Prince Mohammad bin Fahd University, College of Engineering, Department of Chemical Engineering, Al Khobar, Saudi Arabia

 

General Chemistry, Biochemistry, Analytical Chemistry, Organic Chemistry; Chemistry for Engineers

Bioorganic compounds, antioxidant activity, enzyme activity/inhibition, and biochemical parameters in biological samples, medicinal plants, UV-Spectrophotometry, HPLC, and LC-MS-MS